{"id":"bioemu-2","slug":"bioemu-2","name":"BioEmu-2","orgId":"microsoft","family":"bioemu-2","releaseDate":null,"availability":"announced","openWeights":true,"license":null,"paramsTotal":null,"paramsSource":null,"contextWindow":null,"knowledgeCutoff":null,"modelCardUrl":"https://x.com/FrankNoeBerlin/status/2112472173336240499","hfRepo":null,"modalities":["biology"],"aliases":["BioEmu-2","bioemu2","bioemu 2","bioemu-2","microsoft/bioemu2"],"aliasNote":null,"origin":"tracked","tracked":{"trackedSince":"2026-10-20","announced":"2026-10-20","blurb":"Microsoft Research AI for Science's foundation model for biomolecular structure, dynamics and function, in public preview. It generates ensembles of all-atom 3D structures, including multi-chain complexes, ligands and nucleic acids. Open weights under MIT. Not an LLM.","api":"none","openWeights":"yes","params":{"text":"~500M","source":"Hugging Face model card (\"approximately 500M parameters\")"},"facts":[{"label":"Developer","value":"Microsoft Research AI for Science"},{"label":"Status","value":"Public preview (researcher's post)"},{"label":"Architecture","value":"Diffusion-based all-atom score model (model card)"},{"label":"Inputs","value":"Biomolecular sequence(s), with optional MSA, contact and method conditioning"},{"label":"Weights license","value":"MIT (Hugging Face card and GitHub repo)"},{"label":"Intended use","value":"Research; the card says it is not validated for clinical or patient decisions"},{"label":"API","value":"Not mentioned"}],"sources":[{"kind":"press","title":"Announcement on X by Frank Noé (Microsoft Research), a researcher's post","url":"https://x.com/FrankNoeBerlin/status/2112472173336240499","date":"2026-10-20"},{"kind":"repo","title":"BioEmu-2 on Hugging Face","url":"https://huggingface.co/microsoft/bioemu2","date":"2026-10-19"},{"kind":"repo","title":"BioEmu-2 code on GitHub","url":"https://github.com/microsoft/bioemu2","date":"2026-10-20"}],"firstBenchmark":null},"organization":{"id":"microsoft","name":"Microsoft","slug":"microsoft","country":null,"url":null,"color":"#0078D4","mark":"MS"},"price":null,"answer":{"word":"Pending benchmarks.","scope":"Announced Oct 20, 2026; no independent results yet.","lead":"As of Oct 22, 2026, BioEmu-2 is pending benchmarks on isitsota: announced Oct 20, 2026, with no independent results on the boards we track yet.","confidence":"low"},"status":"PENDING_BENCHMARKS","verdicts":[]}