Is CAPHARD state of the art?Pending benchmarks.Announced Oct 20, 2026; no independent results yet.
Phagos' phage–bacteria interaction model. Given a bacterial genome, it scores how likely each phage is to infect it, either against a phage collection the user uploads or Phagos' reference set of 832 phages, so labs know which pairs to test first. Free to use as a hosted app on Hugging Face; the weights are not released. Not an LLM.
The details so far
- Lab
- Phagos
- Announced
- Oct 20, 2026
- API
- Not yet
- Open weights
- Closed
- Parameters
- About 900M
- Type
- Genomic language model that reads all protein-coding genes of both the phage and the bacterium, with no hand-picked features
- Inputs
- FASTA or FFN files
- Output
- An infectivity score per phage–host pair; Phagos says predictions prioritise lab tests and do not replace them
- Access
- Hosted Gradio app on Hugging Face (phagos-biotech-phagos.hf.space); currently limited to hosts the model can assess with enough confidence
- Name
- Codon-Assisted Phage-Host Automatic inteRaction Discovery (EuroHPC project, 2024–25)
Tags marked unsure are not stated on the lab's own pages.
What would let us call it
Verdicts use only independent boards we already track. Two consecutive snapshots are required before any crown.
- Publicly announced with a source
- Usable by the public (API or weights)
- Listed on an independent board we track
- Enough results for a rank in a category
- Holds across two snapshots (crowns only)
What the lab claims
Self-reported. Shown for context; not used in any verdict.
Lab claim: on Phagos' internal test set of 1,920 phage–host pairs, 45.1% precision at 63.7% recall (score ≥ 0.5) and 64.5% precision at 31.1% recall (score ≥ 0.9).
Sources
LABIntroducing CAPHARD (Phagos)phagos.com/news/introducing-caphard-hugging-face · Oct 20, 2026LABCAPHARD app on Hugging Facephagos-biotech-phagos.hf.space/ · Oct 20, 2026PRESSEmma Scharfmann on Xx.com/EmmaScharfmann/status/2112841642914828755 · Oct 21, 2026Tracking ends Jan 19, 2027 unless the API or weights become available.