Is Omnii-1 state of the art?Pending benchmarks.Announced Oct 20, 2026; no independent results yet.
Radical Numerics' genome language model, pretrained across 28 biological modalities including DNA, RNA, proteins and epigenomics, and adapted to eight applications from regulatory genomics to phage and antibody design. Availability not stated. Not an LLM.
The details so far
- Lab
- Radical Numerics
- Announced
- Oct 20, 2026
- API
- Not yet
- Open weights
- Unknown
- Lab
- Radical Numerics
- Type
- Multimodal genome language model, trained on trillions of tokens of genetic and multiomic data (lab blog)
- Modalities
- 28, including DNA, RNA, proteins, chromatin accessibility, histone modifications, DNA methylation, splicing and gene expression
- Applications
- Eight shown: Genome, Phage, Genetics, Diagnostics, Defense, Rare Earths, Antibody and Cancer Vaccine
- Availability
- Not stated for the model; the blog describes a Defense API for the biodefense application
Tags marked unsure are not stated on the lab's own pages.
What would let us call it
Verdicts use only independent boards we already track. Two consecutive snapshots are required before any crown.
- Publicly announced with a source
- Usable by the public (API or weights)
- Listed on an independent board we track
- Enough results for a rank in a category
- Holds across two snapshots (crowns only)
What the lab claims
Self-reported. Shown for context; not used in any verdict.
Lab claim: outperforms AlphaGenome (and Borzoi) on regulatory-track and variant-effect benchmarks.
Lab claim: Omnii-1-designed bacteriophages were administered to a human patient with an antibiotic-resistant infection under a government-regulated compassionate use program.
Sources
LABRadical Numerics announcement on Xx.com/RadicalNumerics/status/2112581706305962435 · Oct 20, 2026LABThread on X by the Radical Numerics CEOx.com/exnx/status/2112580926651904379 · Oct 20, 2026LABIntroducing Omnii-1 (Radical Numerics blog)radicalnumerics.ai/blog/omnii-1 · Oct 20, 2026Tracking ends Jan 18, 2027 unless the API or weights become available.